Diazepam is the commonest benzodiazepine used in dogs and cats to reduce motor action and permit placement of an IV catheter.
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Doses of diazepam are advisable to get about 50 % of those presented to youthful individuals, and procedure limited to a most of two months. Prolonged-performing benzodiazepines including diazepam are certainly not advised for that aged.[19] Diazepam can also be dangerous in geriatric sufferers owing to an important elevated threat of falls.[61]
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Liquor together with diazepam may possibly cause a synergistic improvement on the hypotensive Homes of benzodiazepines and Liquor.[94]
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The standard safeguards are indicated for severely depressed sufferers or Individuals in whom There's any proof of latent depression or nervousness connected to despair, significantly the recognition that suicidal tendencies may be existing and protective steps can be necessary.
Benzodiazepine treatment should be discontinued immediately by a slow and gradual dose reduction routine.[19][77] Tolerance develops for the therapeutic effects of benzodiazepines; by way of example tolerance takes place on the anticonvulsant outcomes and as a result benzodiazepines will not be generally advised for the extensive-phrase management of epilepsy. Dose improves might overcome the consequences of tolerance, but tolerance could then establish to the upper dose and adverse results might increase.